About Dr Tziotzios

Consultant Dermatologist specialising in Scalp and Hair Disorders

Biography

Dr Christos Tziotzios is a Consultant Dermatologist at St. John’s Institute of Dermatology, Guy’s and St Thomas’ NHS Foundation Trust and adjunct Reader in Clinical and Molecular Dermatology at King’s College London. He is also Service Lead for the St. John’s Hair & Nail Clinic.

He graduated from the University of Cambridge and completed integrated academic training (NIHR Academic Clinical Fellowship) in Dermatology at St. John’s Institute of Dermatology. During his NIHR-funded Doctorate, he undertook genetic studies which provided novel mechanistic insight into an immune-mediated and scarring form of alopecia affecting almost exclusively women. The work was published in Nature Communications and led to the identification of novel pathways with potential for therapeutic intervention. His research was further acknowledged with several prizes including the British Association of Dermatologists (BAD) Whimster Prize, the BAD Wycombe Prize, the Royal Society of Medicine Dermatology Research Prize and the NIHR/BAD Award.

He currently holds a prestigious Medical Research Council (MRC) Clinical Academic Research Partnership (CARP) award and a British Skin Foundation (BSF) Young Investigator Award, for ongoing work in follicular biology and lichenoid inflammation with a focus on frontal fibrosing alopecia.

He has been national Chief Investigator for the ALLEGRO trials in alopecia areata (leading to the first NICE-approved, licensed treatment for alopecia); Chief Investigator for the REDWOOD study in alopecia areata; Chief Investigator for the Alopecia+Me (alopeciame.org) and Alopecia+us (alopeciaus.org) studies; he co-leads a national research network into the genetics of polysensitisation; and is Chief Investigator of the FFA-TREAT study, which looks to evaluate routine clinical care in frontal fibrosing alopecia.

Dr Tziotzios teaches, supervises and is examiner for undergraduate and MSc students at King’s College London and has been supervising postgraduate researchers.

Selected Publications

Publication Journal Year PMID
Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02

Tziotzios et al

Free PMC article.
Nat Commun 2019 PMID 30850646
Safety and early efficacy outcomes for lentiviral fibroblast gene therapy in recessive dystrophic epidermolysis bullosa

Lwin SM, et al – Among authors: Tziotzios C

Free PMC article
JCI Insight 2019 PMID 31167965
Nail lichen planus

Tziotzios C, et al.

J Am Acad Dermatol 2019 PMID 30682393
Lichen planus and lichenoid dermatoses: Clinical overview and molecular basis

Tziotzios C, et al.

J Am Acad Dermatol 2018 PMID 30318136
Lichen planus and lichenoid dermatoses: Conventional and emerging therapeutic strategies

Tziotzios C, et al.

– review
J Am Acad Dermatol 2018 PMID 30318137
Congenital Anonychia and Uncombable Hair Syndrome: Coinheritance of Homozygous Mutations in RSPO4 and PADI3

Hsu CK, et al. Among authors: Tziotzios C.

Free article
J Invest Dermatol 2017 PMID 28087452
Tissue and Circulating MicroRNA Co-expression Analysis Shows Potential Involvement of miRNAs in the Pathobiology of Frontal Fibrosing Alopecia

Tziotzios C, et al.

Free article.
J Invest Dermatol 2017 PMID 28774594
Finasteride is of uncertain utility in treating frontal fibrosing alopecia

Tziotzios C, et al.

J Am Acad Dermatol 2016 PMID 26979373
Frontal fibrosing alopecia: there is no statistically significant association with leave-on facial skin care products and sunscreens

Seegobin SD, et al. Among authors: Tziotzios C.

Br J Dermatol 2016 PMID 27614082
Familial frontal fibrosing alopecia

Tziotzios C, et al.

J Am Acad Dermatol 2015 PMID 26089074
Clinical features and WNT10A mutations in seven unrelated cases of Schöpf-Schulz-Passarge syndrome

Tziotzios C, et al.

Br J Dermatol 2014 PMID 24902757
Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA

Lindhurst MJ, et al. Among authors: Tziotzios C.

Free PMC article
Nat Genet 2012 PMID 22729222
Cutaneous scarring: Pathophysiology, molecular mechanisms, and scar reduction therapeutics Part I. The molecular basis of scar formation

Profyris C, et al. Among authors: Tziotzios C.

– Review
J Am Acad Dermatol 2012
Cutaneous scarring: Pathophysiology, molecular mechanisms, and scar reduction therapeutics Part II. Strategies to reduce scar formation after dermatologic procedures

Tziotzios C, et al.

– Review
J Am Acad Dermatol 2012 PMID 22177632
A true positive nasal nodule

Tziotzios C, et al.

Am J Med 2012 PMID 22482858
More than just a big thumb

Tziotzios C, et al.

QJM 2011 PMID 21106503
Swelling scars

Tziotzios C and Burden D.

QJM 2011 PMID 20400442
Leukemia cutis

Tziotzios C and Makrygeorgou A.

Cleve Clin J Med 2011 PMID 21460127